Abstract
Rare diseases known as systemic vasculitides involve the inflammatory destruction of blood vessels, leading to complex disorders that can affect a single organ or multiple organs and systems. The challenges in diagnosis, coupled with the lack of awareness among healthcare providers, particularly primary care physicians, and delayed treatment, often result in disability and worsen the prognosis of systemic vasculitis patients. We have conducted a comprehensive research approach to understand the features of systemic vasculitis, considering demographic, clinical, and laboratory data in Kazakhstan (Shymkent city and the Turkestan region). This approach, which encompasses a retrospective research method, an analytical research method, and a one-stage cross-examination (online survey), is essential in our quest to improve the understanding and management of systemic vasculitis in Kazakhstan.