Abstract
Currently, hypothyroidism is emerging as a significant issue worldwide. According to statistics, the global incidence of hypothyroidism is second only to diabetes. Various types of iodine deficiency diseases are recognized, including hypothyroidism, endemic goiter, hyperthyroidism, thyroid cancer, etc. The prevalence of hypothyroidism ranks first in Kazakhstan. Changes in the level of thyroid hormones during the reproductive period can also significantly impact the expectant mother and the developing fetus. Many chemicals that pollute the environment inhibit protective immunophysiological mechanisms, reduce the body’s ability to adapt, increase the frequency of reproductive system diseases, and alter their course. A decrease in the quality of the environment, social discomfort, and large man-made disasters lead to environmentally dependent transitions and pathological changes in various organs and systems of a person, resulting in a decrease in life expectancy. In this regard, improving the health of the population is an important issue in medicine. In this article, a comparative analysis of the development of hypothyroidism in pregnant women in Almaty and Aktobe was carried out.