Abstract
The purpose of research is a comparative characterization of inhalation and inhalation-epidural anesthesia influence on the state of the cellular mechanisms of antitumor immunity in patients with malignant tumors of the gastrointestinal tract. The study included 181 patients with gastric cancer, pancreatic cancer, who received radical surgery aged 40-70 years. Indices of immune system cellular component in relation to anesthesia - inhalation anesthetic sevoflurane or a combination of inhalation and epidural anesthesia - at 3 and 7 days after surgery were evaluated. The study revealed the Reduction of negative effects of surgery and anesthesia on cell component of the immune system during the application of the combined method of inhalation anesthesia.