Innovative drug delivery technologies in myocardial infarction therapy

2023

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DOI 10.51582/interconf.19-20.11.2023.036
Data confidence 70 medium
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Abstract

Research in the treatment of myocardial infarction is focused on exploring various drug delivery methods and molecular agents to improve cardiac function and reduce scar formation. MicroRNAs miR-19a/19b, members of the miR-17-92 cluster, show potential as therapeutic targets by stimulating cardiomyocyte proliferation and inhibiting inflammatory responses in the heart. Liposomes, as potent drug carriers, provide controlled and targeted drug delivery, improving treatment efficacy. Polymers, including PLGA, and biological polysaccharides such as chitosan and alginate provide versatile carriers for drug delivery, including inhibitors and growth factors, helping to suppress inflammation. Gold nanoparticles have anti-inflammatory and regenerative properties, helping to reduce myocardial infarction and suppress fibrosis. These approaches present new perspectives for the treatment of myocardial infarction and improvement of cardiac function.