MOLECULAR GENETIC CHARACTERISTICS OF A HIGHLY PATHOGENIC AVIAN INFLUENZA STRAIN А/MUTE SWAN/MANGYSTAU/9421/2022 ISOLATED FROM BIRDS WINTERING ON THE COAST OF THE CASPIAN SEA

B.T. Baikara, Yermukhammet Kasymbekov, Yelizaveta Khan, Klara Daulbayeva, Sardоr Nuralibekov, Temirlan Sabyrzhan, Sasan R Fereidouni, Kobey Karamendin, Aidyn I. Kydyrmanov

2023

Data confidence 70 medium

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Abstract

В данной статье представлены результаты сравнительного молекулярно-генетического анализа полного генома высокопатогенного вируса гриппа A А/Mute swan/Mangystau/9421/2022 (H5N1). Исследование проведено на изоляте, полученном от погибшего лебедя-шипуна (Cygnus olor) во время вспышки инфекции среди водоплавающих птиц, зимующих на Мангистауском прибрежье Каспия. В результате исследования данный изолят определен как высокопатогенный штамм, относящийся к Н5 клада 2.3.4.4b. This article presents the results of a comparative molecular genetic analysis of the entire genome of the highly pathogenic influenza A virus A/Mute swan/Mangystau/9421/2022 (H5N1). The study was carried out on an isolate obtained from a dead mute swan (Cygnus olor) during an outbreak of infection among waterfowl wintering on the Mangistau coast of the Caspian Sea. As a result of the study, this isolate was identified as a highly pathogenic strain belonging to the H5 clade 2.3.4.4b.