Abstract
Necrobacteriosis of cattle causes significant economic damage to the animal husbandary, which consists of a decrease in milk productivity, a decrease in fulness, lost weight and productivity and the cost of treating sick animals [1]. Annual studies show that in many farms of the republic, purulent - necrotic diseases of the limbs in cattle and small cattle are widespread. In some farms, especially in the northern and eastern regions of the republic, the incidence of cows with necrobacteriosis reaches 30–56% of the total population [2]. Necrobacteriosis is characterized by purulent-necrotic lesions of the skin, mucous membranes of the underlying tissues, sometimes parenchymal organs; while, as a rule, distal parts of the limbs are affected. This infection affects all types of domestic animals and most wild animals. Cattle are most susceptible, especially pregnant heifers and dairy cows. Young animals are much more sensitive than adult animals[5]. Necrobacteriosis is a disease of the hooves of cattle caused by the pathogen Fusobacterium necrophorum. This disease is quite common both on large and small farms, and the fight against it remains an urgent problem due to the unsystematic use of antibiotics, resistance of the pathogen to drugs occurs, immunity decreases, and the treatment of infection is a laborious process [2, 4]. Necrobacteriosis affects many animal species, affecting various body systems [1]. The diagnosis of the disease was made in a complex manner, taking into account clinical signs and laboratory results. According to the results obtained, the isolated cultures, two isolates, according to morphological, cultural-physiological and biochemical properties, are attributed to the pathogen Fusobacterium necrophorum. The affiliation of the isolated pure culture of necrobacteriosis was determined by the determinant of bacteria of Bergi (1997).As a result, it was found that the causative agent of necrobacteriosis and the accompanying microflora were the most sensitive to tetracycline.