Abstract
Objective: The purpose of this study is to investigate the influence of the biochemical composition of human native ejaculate on the preservation of male gamete activity after the application of cryopreservation technology and to evaluate the potential practical application of these findings in future fertilization processes. Methods: The methodology employed in this study involves a systematic analysis of the technological aspects of cryopreserving human semen, coupled with an analytical examination of how the biochemical composition of semen affects the preservation of male gamete activity. Results: The results of the study demonstrate a clear relationship between the activity of male gametes and changes in the biochemical composition of semen following cryopreservation. Conclusion: This study addresses the issue of male infertility in Kazakhstan and underscores the importance of research in embryology and reproductive medicine to effectively address this problem.