Abstract
Cancer is the name given to abnormal and unregulated growth of cells which multiply in an uncontrolled and unabated way and, in some cases, to metastasize.Colorectal cancer (CRC) is a dreadful health problem worldwide.Tumor markers are assuming an important role in all aspects of cancer care and have an impact on early diagnosis, prognosis and screening for malignancy in asymptomatic groups.There is no "universal" tumor marker that can detect all types of cancer.Our study was case control study including patients attending to Department of Surgical Oncology and Biochemistry, Faculty of Medicine, West Kazakhstan Marat Ospanove State Medical University Aktobe Kazakhstan.50 CRC patients, with no other cancer, 19 males (38%) and 31 females (62%), their ages between 20-70 years were studied.The present study demonstrated that the mean age value for 50 studied CRC patients was 52.9 ± 10.54 years.Carcinoembryonic antigen (CEA) showed a highly statistically significant difference between cases and controls.In the present study, the serum levels of tumor marker CEA were statistically higher in diagnosed cases of colorectal carcinoma as compared to the controls showing the importance of the CEA marker in colorectal cancer.Findings of this study further strengthen the position of tumor markers in diagnosis, prognosis and detection of recurrences of the tumor.