CARDIOMETABOLIC RISK PREDICTION IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE COMBINED WITH SUBCLINICAL HYPOTHYROIDISM

Olena Vadymivna Kolesnikova, Olena V. Vysotska, A. V. Potapenko, Anastasiia O. Radchenko, Anna Trunova, N. G. Virstyuk, Liudmyla Vasylevska-Skupa, Aliya Kalizhanova, Nazerka Mukanova

2023

Full text Open access: Gold Metadata (CSL-JSON)

DOI 10.35784/iapgos.3654

Data confidence 70 medium

How this score is calculated

It is built from checkable properties of the record itself: whether the article has a DOI, how many independent sources confirmed its data, whether the required fields are filled in, and how recent the latest confirmation is. Disagreement between sources and a missing identifier lower it. A value of 80 or above means the record was published without further checking; 60 to 79 means it is published at reduced confidence, with a manual check advisable. A record verified by an editor by hand is never pushed below 90 by a recalculation. This scores our data about the article, not the article itself.

Abstract

One of the most common diseases of our time is non-alcoholic fatty liver disease (NAFLD). Recently published research results indicate that patients with NAFLD along with traditional risk factors for cardiovascular diseases (CVD) have "new" risk factors such as endothelial dysfunction (ED), carotid intima-media thickness (CIMT), an increase in the CRP level, as well as risk factors combined into the Framingham scale. It is also known that combination of NAFLD with subclinical hypothyroidism (SH) forms an abnormal metabolic phenotype, which is associated with cardiometabolic risk factors. The study of cardiometabolic predictors and vascular markers in patients with NAFLD in combination with SH will provide an opportunity to improve the strategy of cardiovascular events prevention in such comorbid patients.