APPLICATION OF MOLYBDENUM-BASED BIOSENSORS IN THE DIAGNOSIS OF DISEASES

2023

Closed access Metadata (CSL-JSON)
DOI 10.53511/pharmkaz.2023.71.77.007
Data confidence 70 medium
How this score is calculated

It is built from checkable properties of the record itself: whether the article has a DOI, how many independent sources confirmed its data, whether the required fields are filled in, and how recent the latest confirmation is. Disagreement between sources and a missing identifier lower it. A value of 80 or above means the record was published without further checking; 60 to 79 means it is published at reduced confidence, with a manual check advisable. A record verified by an editor by hand is never pushed below 90 by a recalculation. This scores our data about the article, not the article itself.

Abstract

Molybdenum transition metal compounds and nanoparticles have attracted much attention due to their unique physicochemical properties, multifunctional properties, and increased technological applications. This literature review reviewed the work of molybdenum compound biosensors based on research conducted over the past five years. Biosensors are analytical devices that combine a biological component and a physico-chemical component to produce a measured signal. In the course of the literature review, it was found that molybdenum-based biosensors were used to determine troponin-I, chronic myeloid leukemia, cyclic citrulline peptide, acetaminophen, Tau-381, dopamine, and epithelial cell adhesion molecules. It was found that these sensitive biomarkers are very effective for diagnosis, predicting the rate of development of the disease and rehabilitation, evaluating pharmacological treatment - one of the main obstacles in the study of diseases such as acute myocardial infarction, arthritis, cancer and Alzheimer's disease. As a result of the considered scientific works, such basic parameters of molybdenum-based biosensors as the detection limit relative to synthesis methods, electrochemical analysis methods, specificity, and the analysis under study were compared in tabular form. In general, the main purpose of this review is to conduct an analysis and a comprehensive review of the research work of molybdenum and its compounds used in the creation of a biosensor.