ACUTE RENAL DISORDER IN PATIENTS WITH ACUTE LEUKEMIA AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION: A SERIES OF CLINICAL CASES

A. MURZAKHMETOVA, Vadim Kemaykin, Ayagul M. Ainabay, Assel Meiramova, Bayan A. Ainabekova

2022

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DOI 10.52532/2521-6414-2022-3-65-32-36
Data confidence 70 medium
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Abstract

Relevance: Acute renal kidney disorder is a serious complication in patients with acute leukemia who underwent hematopoietic stem cell transplantation (HSCT). According to statistics, acute renal dysfunction often occurs in the first 100 days after HSCT. This study aimed to evaluate kidney function in patients with acute leukemia after hematopoietic stem cell transplantation. Methods: The article presents clinical cases of patients with acute lymphoblastic leukemia who developed acute renal failure after HSCT. The dynamics of the functional state of kidneys in patients with acute lymphoblastic leukemia after HSCT are described. Results: The acute kidney disorder in the studied patients was mainly caused by HSCT complications. We have identified renal kidney damage in the form of acute tumor lysis and thrombotic microangiopathy. Conclusion: Patients with acute lymphoblastic leukemia risk developing acute kidney disorder during HSCT, which requires careful monitoring of kidney function, especially in the early post-transplant period.