Abstract
The problem of treatment and prevention of acute intestinal infections is urgent in all countries without exception. The strain Saccharomyces cerevisiae Az-12, isolated from the juice of pomegranate, grown in the Turkestan region, shows the features of the probiotic culture Saccharomyces cerevisiae var. boulardii. Saccharomyces cerevisiae Az-12 antago nistic abilities were studied with the following conditionally pathogenic or pathogenic bacteria: Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus as the most common bacteria associated with diarrhea diseases. Saccharomyces cerevisiae Az-12 has a distinct inhibitory relationship to Staphylococcus aureus and Escherichia coli. It has been proven that probiotic activity of Saccharomyces cerevisiae Az-12 against human pathogens is due to a decrease in bacterial growth and due to the adherence of bacteria to the walls of yeast cells. Probiotic yeast cultures Saccharomyces cerevisiae var. boulardii Az-12 can be used as a preventive and therapeutic agent for the treatment of various diarrheal diseases