Changes in the antioxidant system under the action of radiation in the long term period

A.A. Alenova, O.Z. Ilderbayev

2019

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DOI 10.32523/2616-7034-2019-127-2-8-16
Data confidence 70 medium
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Abstract

The aim of the study was to study changes in the antioxidant system of immunocompetent organs and cells when exposed to sublethal doses of gamma radiation in the long term. The study was conducted on 40 male rats divided into 4 groups: group I- intact, group II– research after seven days of irradiation, group III– research after thirty days of irradiation and group IV– research after ninety days of irradiation. On the 7th and 30th days of the study, after high-dose γ-radiation in the studied organs, a sharp decrease in the activity of enzymes of the antioxidant system was noted, and on the 90th day, i.e. in the remote period of irradiation, inhibition of the activity of a greater degree of the catalase enzyme remains.