A systematic review of the occupational burden of chronic obstructive pulmonary disease in the Commonwealth of Independent States

Denis Vladimirovich Vinnikov, Tatsyana Rybina, Leonid Aleksandrovich Strizhakov, Sergey Anatolievich Babanov, Irina Y. Mukatova

2021

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DOI 10.1183/13993003.congress-2021.pa3351
Data confidence 70 medium
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Abstract

Background: Very little is known in the West about the contribution of hazardous occupations in chronic obstructive pulmonary disease (COPD) in the Commonwealth of Independent States. The aim of this review was to systematically analyze published population-based studies from the CIS and ascertain the occupational burden of COPD in the region. Methods: We searched www.elibrary.ru and Pubmed for population-based studies in nine countries since their commencement. Eligible studies were then included in the meta-analysis producing the the odds of COPD from vapors, dusts, gases or fumes (VDGF), whereas the population attributable fraction percent (PAF%) was pooled with meta-proportion. Results: There were too few studies from the region. Three studies from Russia, one from Kazakhstan and one more from Azerbaijan and Kazakhstan (total N=18908) only were published from 2014 to 2019 and included in the analysis. COPD was confirmed with spirometry in four of them. The pooled odds ratio (OR) of COPD from VGDF was 1.69 (95% confidence interval (CI) 1.34;2.13). OR of COPD from VGDF was 1.96 (95% CI 1.35;2.85, N=2 studies) in Kazakhstan and 1.52 (95% CI 1.13;2.05, N=2 studies) in Russia. The pooled PAF% was 6% (95% CI 2; 14%). Conclusions: For a large territory of nice countries of CIS, there were too few population-based studies published so far. Only three of nine CIS countries published evidence of the association in the population-based studies, calling for the remaining six countries to provide evidence from their territories.