INTERFERON STATUS OF ENDOMETRY IN PATIENTS WITH MISCARRIAGE AND “THIN ENDOMETRY” SYNDROME

Н.М. Мамедалиева, Аlmagul Kurmanova, Gaini Anartayeva, Gaukhar Moshkalova

2020

Full text Open access: Gold Metadata (CSL-JSON)

DOI 10.37800/rm2020-1-33

Data confidence 70 medium

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Abstract

The article presents the results of examination of 21 patients with miscarriage and “thin endometry” syndrome compared with 20 patients without reproductive losses and the presence of normal endometrial thickness. Interferon gamma intracellular production by cytotoxic endometrial lymphocytes was investigated by flow cytofluorometry. Based on the study, it was found that in patients with miscarriage and “thin endometry” syndrome, the interferon gamma intracellular production by cytotoxic CD8+ lymphocytes was sharply suppressed by almost 36 times, by CD56+ lymphocytes - by 13 times, by CD16+ lymphocytes - by 4.5 times.