Abstract
To study the role of connective tissue dysplasia syndrome in children in the occurrence of oral diseases. 104 children with oral cavity pathology were on treatment during 2019-2020 in hospital. Aged from 5 to 17 years. All children had diseases of the digestive tract, were on dynamic observation at primary health care level. The control group consisted of 36 almost healthy children. comparable in age and sex. verified diagnosis, patient consent, absence of concomitant decompensated and sub compensated states. Connective tissue dysplasia of the oral cavity was more often in the control group (54.8%) comparing with the comparison group (19.4%, p<0.05), and more often among boys (32.6%) compared with girls (22.1%). The most common stigmas: gothic palate (26.2%), flat palate (21.5%), impaired growth and development of the jaws (24.5%), abnormalities in the permanent teeth eruption (11.3%), short frenum of the tongue (10.4%), folded tongue (6.1%). The level of stigma in 45.6% of children - 3 stigmas, 31.6% - 3–4 stigmas, and 22.8% - more than 5 oral stigmas. Among the children of the comparison group, the most common was the gothic palate (11.1%, p<0.05), short frenum (5.5%, p<0.05), flat palate (2.8%, p<0.05). Probably, a significant prevalence of connective tissue dysplasia of the oral cavity organs, formed prenatally, can be markers of chronic somatic diseases.