Abstract
Blood transfusion therapy in cancer patients: Modern aspects (literature review)Relevance: Anemia is a common syndrome in cancer patients, and blood transfusion is the most common treatment for anemia.Anemia and blood transfusion are associated with worse clinical outcomes.The efficacy and safety of different blood transfusion strategies are unclear.The study aimed to analyze current blood transfusion strategies in oncology.Results: In most clinical situations, a restrictive strategy showed efficacy and safety.However, low perioperative hemoglobin level is associated with increased mortality and complication rates.Several clinical trials demonstrated the benefits of liberal strategy; it may be due to comorbidities and low compensatory ability.Conclusion: Anemia in cancer patients is associated with worse clinical outcomes.Current blood transfusion strategies in oncology follow a restrictive approach based on the likelihood of blood transfusion complications.Oncology patients represent a challenging population that requires a personalized approach to perioperative anemia management.