The Risks of Chronic Internal Diseases Among the Workers of Uranium Processed Enterprise in Kazakhstan

Farida Bekenova, Aigul Abduldayeva

2012

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DOI 10.1096/fasebj.26.1_supplement.859.16
Data confidence 70 medium
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Abstract

Data on the prevalence rate of chronic internal diseases (CID) among the nuclear industry workers are scarce and contradictory. The aim of the study was to investigate the prevalence rate and relative CID risks among the workers at uranium processed company who are affected by occupational radiation‐chemical effects of low intensity. It was studied the prevalence (Pr), relatively rough (RR) CID risks among 912 workers at Hydrometallurgical Plant ‐ plants for the production of nitrous oxide ‐ uranium oxide. Comparative group was consisted of 788 workers at bearing plant (BP). The most common CID were arterial hypertension (AH)‐24.7%, chronic gastritis (CG)‐17.4%, chronic bronchitis (CB)‐19.3%. These diseases have excess RR gmzvspz (p<0,0001):AH‐2.4(95%CL1,9–3,0); CG‐2.1(95%CL1,6–2,7), CB‐2.0(95%CL 1,6–2,6;). A more accurate judgments about excess Pr disease is possible on the basis of SRR assessment (the method of stratification), which allows to monitor the confounding effects. Specific confounding for hypertension are heredity, obesity, metabolic syndrome, alcohol abuse, high anxiety, addiction to salty foods, and for CG‐H.pylori; for HB ‐ smoking. Thus, standardized for sex, age, seniority and the main predictors, relative risks were higher than the rough risks, which confirms the increased risk of hypertension, CG, CB in terms of combined radiation and long‐term chemical exposure.