Screening for early detection of stomach cancer in Kazakhstan: first results

Galiya Orazova, Leonid Karp, Alikhan Kh Dosakhanov

2015

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DOI 10.1096/fasebj.29.1_supplement.lb682
Data confidence 70 medium
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Abstract

Introduction Over the last 15 years (1999‐2013) more than 42 thousand patients have been registered with stomach cancer (SC) identified for the first time. Materials and methods In 2013, screening was introduced in Kazakhstan with the aim of early detection of stomach and esophageal cancers. The target population is persons aged 50‐60 years. Screening by endoscopic examination was conducted in a pilot mode in 4 regions and in Astana and Almaty cities. Results 150,546 persons were examined in the targeted age groups.1,649 patients were identified with disorder of gastro‐intestinal tract mucosa (0.9% from examined patients), of whom 1,589 people (96.4%) were registered for medical checkup. Statistically significant differences of endoscopic esophageal and stomach disorders frequency were identified between max (2.8%) and min (0.4%) parameters (p<0.05). The frequency of the disorder was the highest in the age group of 60 years. According to the data of primary medical care the diagnosis of SC was achieved in 87 cases (0.05%). According to the endoscopic examination 79 cases of SC were identified (including 39 morphologically verified). According to the cancer registry, SC detectability is 0.04% from the number of examined patients. Complete agreement between primary medical care and cancer‐register data was observed only in one region. SC is identified more frequently at stage II (47.0%). Conclusions According to the primary medical care and cancer registry data, there is mismatch in the results: almost in all regions both cases of stomach cancer over diagnosis in some regions and misreporting in others.