Abstract
The paper presents the results of the analysis of epidemiological, clinical and laboratory data, evaluation the effectiveness of etiologic and pathogenetic therapy in children with chronic hepatitis C (CHC). Among the observed children the prevalence of a vertical transmission of the hepatitis C virus has been shown. The experimental data of the study of the pathogenesis published by domestic and foreign researchers in comparison with the results of the conducted analysis are presented. The highest probability of replicative mechanism in the pathogenesis of CHC in children has been shown, as well as an indirect role of allergic factors in the etiopathogenesis of CHC.