Cover Feature: Three‐Component Castagnoli‐Cushman Reaction of 3‐Arylglutaconic Acid Anhydrides, Carbonyl Compounds, and Ammonium Acetate: a Quick and Flexible Way to Assemble Polysubstituted NH‐δ‐lactams (Eur. J. Org. Chem. 11/2021)

2021

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DOI 10.1002/ejoc.202100298
Data confidence 70 medium
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Abstract

The Cover Feature shows the synthesis of NH-δ-lactams through three-component Castagnoli–Cushman reaction of 3-arylglutaconic anhydrides with carbonyl compound and ammonium acetate. The way chemical building blocks are united to form the desired heterocyclic product is compared to the famous tile-matching Tetris game. More information can be found in the Communication by M. Krasavin et al.