Mercury exposure and its effects on fertility and pregnancy outcome

Geir Bjørklund, Salvatore Chirumbolo, Maryam Dadar, Lyudmila M. Pivina, Ulf Lindh, Monica Butnariu, Jan Aaseth

2019

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DOI 10.1111/bcpt.13264
Data confidence 85 high
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Abstract

Mercury (Hg), a highly toxic environmental pollutant, shows harmfulness which still represents a big concern for human health, including hazards to fertility and pregnancy outcome. Research has shown that Hg could induce impairments in the reproductive function, cellular deformation of the Leydig cells and the seminiferous tubules, and testicular degeneration as well as abnormal menstrual cycles. Some studies investigated spontaneous abortion and complicated fertility outcome due to occupational Hg exposure. Moreover, there is a relation between inhaled Hg vapour and reproductive outcome. This MiniReview evaluates the hypothesis that exposure to Hg may increase the risk of reduced fertility, spontaneous abortion and congenital deficits or abnormalities.