Abstract
Introduction: Fibrolamellar carcinoma is a rare primary hepatic malignant tumour, which was first described as a pathological variant of hepatocellular carcinoma. Aim: The aim of the paper is to discuss the case report of surgical treatment of a multicentric form of presumably fibrolamellar carcinoma significantly exceeding the Barcelona Clinic Liver Cancer staging system criteria, although tumour size and multi-organ lesions are not a contraindication to resection. Case study: This case report is an original one because the surgical intervention was performed on a patient with a multicentric fibrolamellar hepatocellular carcinoma with the initial foci of 16.0 × 12.0 × 9.0 cm and 10.5 × 8.7 × 7.5 cm. Results and discussion: The surgical intervention (right hemihepatectomy, lymphatic dissection D2) was performed as an independent treatment without prior chemotherapy. Conclusions: The surgical treatment occurred 5 years ago, and at the time of writing there has been no relapse and no sign of progression.