Abstract
One of the frequent violations of the salt balance in patients with a neurosurgical profile is hypernatremia, which is a consequence of brain edema. The purpose of this work was to compare the effectiveness of correction of hypernatremia of Central origin in patients with neuro-resuscitation profile by using hypotonic 0,45 % solutions of sodium chloride and sterofundin solution in the complex therapy of brain edema. 2 groups of patients were examined: the main group (n = 16), who received hypotonic solutions (0,45 %) of sodium chloride for the purpose of correcting hypernatremia as part of anti-edema therapy, and the control group (n = 13), which used a sterofundin solution for this purpose. After the analysis, the dynamics of blood CBS indicators in patients of both the first group and the second group did not undergo statistically significant differences in results at admission to the hospital (ICU) and during intensive decongestant therapy, which allowed us to conclude that the minimal effect of the solutions used for the correction of hypernatremia on the blood carbonate buffer system.