Hospital-based surveillance for encephalitis and meningitis in South Kazakhstan oblast

2019

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DOI 10.1016/j.ijid.2018.11.222
Data confidence 70 medium
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Abstract

Purpose: Encephalitis and meningitis (EM) are severe infections of the central nervous system associated with high morbidity and mortality. In Kazakhstan, 33% to 77% of hospitalized EM cases are of unknown etiology. While cases with clinical symptoms of EM undergo routine culture for bacterial pathogens including Neisseria meningitides, PCR has been infrequently used to identify viruses or bacteria missed by culture.