CHANGE OF WALL THICKNESS OF MIOCARDIUM WITH ARTERIAL HYPERTENSION ACCORDING TO MORTEM EXAMINATION BY ETHNICITY (BETWEEN KAZAKH AND RUSSIAN HYPERTENSION PATIENTS)

Aiman Kerimkulova, Вебер Виктор Робертович, Natalya Latypova, A. Ospanova

2018

Closed access Metadata (CSL-JSON)
DOI 10.1097/01.hjh.0000539722.96633.a7
Data confidence 70 medium
How this score is calculated

It is built from checkable properties of the record itself: whether the article has a DOI, how many independent sources confirmed its data, whether the required fields are filled in, and how recent the latest confirmation is. Disagreement between sources and a missing identifier lower it. A value of 80 or above means the record was published without further checking; 60 to 79 means it is published at reduced confidence, with a manual check advisable. A record verified by an editor by hand is never pushed below 90 by a recalculation. This scores our data about the article, not the article itself.

Abstract

Objective: To study the ethnical features of left and right ventricles of the heart remodeling among patients who died after suffering from hypertension during the lifetime according to mortem examination in Semey (Kazakhstan). Design and method: A retrospective study was conducted, which explored the autopsy protocols of patients suffered from hypertension that died during the sixteen-year period (from 1999 to 2014) in Semey, Kazakhstan. To analyse the available data in the study group, the values were taken that defined the parameters of the left and right ventricles at the time of autopsy. The normal wall thickness of the left ventricle (without papillary muscle) had the value of 0.7–1.2 cm, the right ventricle - 0.2–0.3 cm. We studied the changes in cardiac remodelling of the two most numerous study groups among Russian and Kazakh population. Results: A mortem examination cardiac remodeling processes among patients with hypertension was conducted based on 674 data representing 407 male and 267 female, 208 Kazakh, 437 Russian and 29 other nationalities. The average age was 54.02 ± 11.84 (M+SD). Our analysis of those autopsy protocols of patients, who were suffering from hypertension and who died suddenly, showed that there were different changes in the settings of the left and right ventricles. Differences have been identified based on ethnicity. Right ventricular hypertrophy was detected in 86.9% of cases. When comparing the right ventricular wall thickness among Russian and Kazakh, statistically significant difference (p = 0.001) was found, using the criterion of Mann-Whitney U at a significance level of 0.05. Categorical data were compared using chi-squared tests. The presence of right ventricular hypertrophy was detected among ethnic Russians in 90.5% (n = 382), ethnic Kazakhs – 78.9% (n = 153), Chi-square Pearson 15.81, p < 0.001. Conclusions: High prevalence of having right ventricular hypertrophy (up to 86.9%) was identified among patients suffering from hypertension. Moreover, there is statistically significant difference in the thickness of the wall of the right ventricle by ethnicity. Greater distribution of right ventricular hypertrophy was observed in Russian population than Kazakh.