OPTICAL AGGREGOMETRY IN THE EVALUATING OF ANTIPLATELET THERAPY EFFECTIVENESS

2017

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DOI 10.25555/thr.2017.4.0817
Data confidence 70 medium
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Abstract

В настоящей статье изложены клинические случаи с определением функции тромбоцитов методом оптической агрегометрии на фоне лечения антиагрегантами. Приведены клинические примеры с результатами агрегатограмм: со стандартными агрегационными кривыми на фоне лечения одним и двумя антиагрегантами. Выявлены случаи резистентности к одному из препаратов, случай с высоким риском кровотечения. Тестирование функции тромбоцитов позволило выявить пациентов высокого риска, провести оценку эффективности и коррекцию антитромбоцитарной терапии. Platelet function in patients taking antiplatelet agents was assayed by optical aggregometry. The clinical cases demonstrated some aggregatograms: standard, under administration of one or two antiplatelet agents as well as the resistance to antiplatelet agents together with high risk of bleeding. Testing of platelet function provided an opportunity to identify patients with high risk as well to evaluate the effectiveness and correction of antiplatelet therapy.