Effect of herbal syrup “Limonidin” at the functional non ulcer dyspepsia

Aizhan I. Zhussupova, EA Izatullayev, KZ Kamytbekova, AV Maulenova, OV Nikolaeva, G.D. Zhussupova

2017

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DOI 10.1055/s-0037-1608593
Data confidence 85 high
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Abstract

The syndrome of the functional not ulcer dyspepsia (FNUD) can be met independently as well as in association with a number of widespread diseases of the digestive system. Main reasons for its emergence are the violations of the motor function of the stomach and duodenum, and also a hypersensibility of stomach wall receptors to stretching. Abundance of complaints, linked to stomach pathology, is very high and occurs in industrialized countries at 30 – 40% rate of the population, and a half of all cases are the share of non ulcer dyspepsia. Clinical trials of domestic herbal syrup “Limonidin” on a syndrome of FNUD are conducted on the basis of scientific and clinical diagnostic center of SRICID on 30 patients (63.3% of which are women), middle age of 41.55 ± 11.82. Patients were included in a research only from their informed consent. Observation was conducted for 21 days. At all patients included in a research the endoscopic study of proximal departments of digestive tract and ultrasound examination of abdominal organs was conducted. In the presence of organic pathology patients were excluded from a research. From the results of the experiment it might be concluded that the studied herbal medicine possesses along with antiinflammatory and antiseptic properties spasmolytic influence on a smooth emasculation of a stomach. Physiological activity of syrup might be defined by presence of epigallocatechin-3,3,5,7,3',4',6'-hexahydroxyflavan, (-)- epigallocatechin-(4β→8)-2R, 3R(-)-epigallocatechin-3, (-)-epigallocatechin-(4β→8)- 3,5,7,3',4',6'-hexahydroxyflavan, myricetin and a number of its glycosides.