Preparation and Evaluation of Biological Activity of the Sublimated and Cryopreserved Forms of the Herpes Virus of Turkeys

2017

Full text Open access: Hybrid Metadata (CSL-JSON)
DOI 10.20546/ijcrbp.2017.409.004
Data confidence 70 medium
How this score is calculated

It is built from checkable properties of the record itself: whether the article has a DOI, how many independent sources confirmed its data, whether the required fields are filled in, and how recent the latest confirmation is. Disagreement between sources and a missing identifier lower it. A value of 80 or above means the record was published without further checking; 60 to 79 means it is published at reduced confidence, with a manual check advisable. A record verified by an editor by hand is never pushed below 90 by a recalculation. This scores our data about the article, not the article itself.

Abstract

The article contains data on the technology of obtaining and biological activity of the freeze-dried and cryopreserved forms of the turkey herpes virus culture used for the manufacture of the vaccine against Marek's disease. Using the methods of stationary and roller cultivation, a culture biomass of the herpes virus of turkeys was obtained, which was subjected to sublimation and cryopreservation in a mixture of two different stabilizing components. The titration results of these two forms of the vaccine showed that the virus titer was maintained at a level sufficient to be used as a vaccine for the immunization of chickens against Marek's disease.