Monitoring of antibiotic therapy in Acute Respiratory Infections (ARIs) complicated with community-acquired pneumonia in children

Bayan Turdalina, A. Seydullayeva, Mazhit Shaidarov, Dinagul Bayesheva, Almagul R. Kushugulova, C. Sujith

International Journal of Infectious Diseases, 2016

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DOI 10.1016/j.ijid.2016.11.133
Data confidence 70 medium
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Abstract

Purpose: To increase the efficiency of antibacterial therapy of ARIs through the use of antibacterial card that allows to carry out the monitoring of antibiotics used in the prehospital phase Methods & Materials: A retrospective analysis of case histories of patients with a clinical diagnosis of ARIs complicated with community-acquired pneumonia in children. Age of children ranged from one month to five years. Patients were treated in viral diseases branch of municipal children's infectious diseases hospital in Astana. Patient's data of antibacterial records were analyzed in outpatient stage in order to monitor antibiotic therapy. We developed an antibiotic map which includes the data on antibiotics obtained before entering the hospital for the last 3 months, indicating the dose and duration of outpatient treatment, as well as antibiotics that the patient received in the hospital, the dose and duration. This card was put into practice in the hospital from 2009. This allows us to track the quantitative and qualitative characterization of antibacterial therapy in hospital. Statistical data calculation was performed using Excel 2010 software and SPSS Statistics 20.0. Results: We analyzed 395 cases patients in the viral disease branch with a clinical diagnosis of ARIs complicated with community-acquired pneumonia. The average age of studied patients was - 20.48 +- 13.95 months. The antibacterial card was revealed that 57 (14.4%) patients out of 395 got antibiotics before hospitalization. At the time of admission, the period from the beginning of illness averaged - 3.2+2.1 days. Among the antibiotics the most commonly used were semi-synthetic aminopenicillin (40.3%), inhibitor protected semi-synthetic aminopenicillin (17.5%), macrolides (15.6%) 2-generation cephalosporins (12.3%), 3rd-generation cephalosporins (8.7%). During the appointment of antibacterial therapy, physician will base on the obtained data in order to avoid irrational use of antibiotics. Conclusion: The use of antibacterial cards, with the aim of monitoring of used antibiotics in the hospital, allowed to improve the quality of the causal treatment, to reduce significantly the time of the patient's stay in hospital and to reduce drug polypharmacy.