Abstract
Piroplasmosis in cows manifests mainly as a violation of erythrocytes, degenerative changes in parenchymal organs, general jaundice, hemosiderosis, and splenic hyperplasia. First, it affects the liver, followed by a violation of the digestive system; then, kidney function is impaired resulting in a breach of toxic substance released from the body. The blood is depleted in the number of erythrocytes, leukocytes, and hemoglobin. From decaying under the influence of parasite, hemoglobin is released from the red blood cells and is partially excreted by the kidneys in urine, resulting in the urine becoming dark red in color (hence, the disease is colloquially called “blood urine”). Hemoglobin part is processed into bile pigments; however, visible mucous membranes (eyes and mouth), skin, and subcutaneous tissue become yellowish.