Synthesis, mechanism of formation and spatial arrangement of (2S,3S,6R)-2,6-diphenyl-3,4-dimethyl-6-ol

2013

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DOI 10.1134/s1070363213120098
Data confidence 70 medium
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Abstract

Alkylation of alkaloid D-pseudoephedrine with bromoacetophenone results in a morpholine derivative. Structural and energy characteristics of the molecules of the starting, intermediate, and final reaction products were calculated by ab initio method in the HF/6-31G(d,p) approximation. The spatial structure of the final reaction product was determined by X-ray diffraction analysis.