Using computational models for development of the three-dimensional visualization in molecular biology

Ravil I. Mukhamediev, Yevgeniya A. Daineko, D. Bari, Almagul T. Mansharipova

2014

Closed access Metadata (CSL-JSON)
DOI 10.1109/icaict.2014.7036006
Data confidence 70 medium
How this score is calculated

It is built from checkable properties of the record itself: whether the article has a DOI, how many independent sources confirmed its data, whether the required fields are filled in, and how recent the latest confirmation is. Disagreement between sources and a missing identifier lower it. A value of 80 or above means the record was published without further checking; 60 to 79 means it is published at reduced confidence, with a manual check advisable. A record verified by an editor by hand is never pushed below 90 by a recalculation. This scores our data about the article, not the article itself.

Abstract

A method for three-dimensional visualization of molecular biology processes modeled by chemical kinetic equations is presented. To implement this visualization, the software in C# and a database of three-dimensional forms that model molecular complexes are developed. The quantitative parameters in this visualization scheme are determined from kinetic equations governing the participating components, so our visualization is not only qualitative but also quantitative. As a case study, it was visualized a mathematical model for mitochondria-dependent apoptosis (programmed cell death) proposed by Bagci et all [19].