Abstract
Introduction: Tobacco products emit different compounds and there is a need to record them to effectively evaluate their toxicology. Methods: Smoke of four different tobacco products, two conventional (Parliament and LM) and two heated (GLO and iQOS) cigarettes (HTP) was analyzed qualitatively. Each product is connected to a 20mL vial with a pump. The smoke of each product was collected for 30s in this vial and analysed using solid-phase microextraction–gas chromatography–mass spectrometry. Each test is replicated three times. Results: Table 1 shows the number of compounds detected in the smoke of each product. Conventional cigarettes smoke contain higher number of Aromatic Hydrocarbons, Alkadienes and Terpenes compared to HTP, while it contains less Alcohols and Esters. Seven of the seventeen Aromatic compounds, all Alkadienes and five Ketones in GLO emissions are not present in the emissions of the two conventional cigarettes while only one Alcohol, one Alkane, one Ester, two Aldehydes and one Terpene is in common. iQOS emissions compared to the conventional cigarettes have different seven Aromatic Hydrocarbons, seven Alcohols, one Acid, four Ketones, all the Alkadienes and the Esters, all except two Aldehydes and all except one Terpene. Conclusions: Conventional cigarettes and heated products differ significantly in the chemical composition of their emissions. A wide variety of compounds present in heated products emissions is not detected in conventional cigarettes emissions and vise versa.