Abstract
We studied the combined effect of gamma radiation (6 Gy, remote period) and emotional stress on immunological reactivity. At the early period of emotional stress, all indicators of the immune system, such as cellular, humoral, and nonspecific phagocytic links of immunity were activated, indicating the activation of the general adaptive syndrome of the organism. The suppressive action of gamma radiation on the immune system was preserved in a remote period, with this suppression being revealed not only on the T-cellular link, but also on nonspecific phagocytic links, and the functional-metabolic activity of neutrophils. In the remote period after the combined effect of sublethal gamma radiation and emotional stress in the early stage of the adaptation syndrome, there was a decrease in all cells of the T-system of immunity, in the functional ability of leukocytes, and in the mononuclear phagocytic system of the body. The experimental emotional-radiation pathological process was accompanied by disorders of the functional activity of the essential adaptive systems of the body. Based on our results, we could conclude about the dominant role of ionizing radiation in immunological reactivity.