Abstract
The article discusses the changes in the cell after the experiment in the bronchoalveolar lavage. According to the results of the examination of rats with dust dusting of industrial cities of the Karaganda region (Karaganda, Temirtau, Balkhash, Zhezkazgan), methods of cytological analysis were used. Cytochemical methods were used for early detection of functional changes in the body's nonspecific defense against environmental factors. Experimental studies of the impact of urban dust in Karaganda, Temirtau, Balkhash and Zhezkazgan indicate the development of a general toxic effect in rats, manifested by changes in the cells of bronchoalveolar lavage, and a violation of the integrity of the cells was established.