Enzootic bovine leucosis in cows on farms in Almaty and Turkestan regions of Kazakhstan

E3S Web of Conferences, 2020

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DOI 10.1051/e3sconf/202017602003
Data confidence 70 medium
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Abstract

The objective of this study was to evaluate pathomorphological and histopathological characteristics of internal organ tissues and skeletal muscles of Black-Motley cows with bovine laeukemia necropsied between 2013 and 2017. Pathomorphological and histopathological assessment of enzootic bovine leukosis was performed. The viral presence was proved by haematological study, enzyme-linked immunosorbent assay and agar-gel immunodiffusion. There was the pathomorphological manifestation of an immunosuppressive condition in the cattle, as well as leukemic cell accumulations in the brain, kidneys, duodenum, spleen, lymph nodes, cardiac and skeletal muscles. Our study is considered to bear significance concerning the description of microstructural changes involving lymph node trabeculae and myocardial fibres from leukemic cows. This investigation, therefore, provides new knowledge on histopathological features of enzootic bovine leucosis, which potentially may bring new insights into the disease mechanisms.