Effect of Vitamin E Deficiency on Oxidative Metabolism and Antioxidant Enzyme Activity of Macrophages

1990

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DOI 10.1159/000177580
Data confidence 85 high
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Abstract

In AUG rats, deprived of vitamin E for 90 days, we noted a 3-fold increase of kinetic parameters of luminol-dependent chemiluminescence of macrophages, stimulated with opsonized zymosan, superoxide dismutase activity decrease and increment of plasma membrane lipid bilayer microviscosity, which was estimated by fluorescent probe pyrene eximerization method. Vitamin E deficiency did not affect glutathione peroxidase and glutathione reductase activities of macrophages.