Voltage-gated Potassium Channels (Kv7): Molecular Structure, Regulation, and Role in Pathogenesis

Engineered Science, 2025

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DOI 10.30919/es1632
Data confidence 70 medium
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Abstract

The potassium channels of the Kv7 family, comprising KCNQ1 to KCNQ5, assume a critical role in the regulation of membrane potential and cellular excitability within the nervous, cardiovascular, sensory, and endocrine systems.Their specificity to distinct tissues makes them associated with a wide range of pathological conditions, including epileptic encephalopathy, long QT syndrome,