Recent advancements in transcriptomics and its application in basic medical and clinical sciences

2024

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DOI 10.12692/ijb/25.3.40-57
Data confidence 70 medium
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Abstract

Transcriptomics or transcriptome profiling emerged as one of the major powerful approaches in the science of medicine and clinical practices.Over the last decades, the application of transcriptome has been significantly applied in oncology, cardiology, gastro infection, and pathogenic diseases.Advancements in sequencing technologies like RNA sequencing, biomarkers, gene signature, expression profiling of genes, and their aberrant expression affect disorders.Further, the application of transcriptomics also includes the discoveries of molecular targeted therapies for numerous disorders.The contribution of transcriptomics in medicine and clinical sciences has revolutionized the understanding of the nature of the disease, biological and molecular pathways, and insight into personalized medicine and therapies for many disorders.This essay could explore the current state of transcriptome technology in medicine and clinical sciences.It could discuss the techniques, such as RNA sequencing, and their potential applications for understanding diseases and developing new treatments.Additionally, the essay could delve into the ethical considerations surrounding transcriptome technology and its use in research and clinical practice.Furthermore, advancement in transcriptomics application may allow standardization and cost reduction analysis which should make transcriptomics one of the significant contemporary in the field of medicine and clinical sciences.