Composition development and biopharmaceutical study of dental films based on peppermint essential oil

2023

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DOI 10.59598/me-2305-6045-2023-107-2-19-22
Data confidence 70 medium
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Abstract

Currently, one of the promising ways to take medicines are instant dosage forms (in particular, medicinal films), which have a number in comparison with traditional dosage forms. This work, a composition of films for dentistry has been developed, which includes peppermint essential oil as the main active ingredient, gelatin, natrium-carboxymethylcellulose (Na-KMC), glycerin, Tween-80 and purified water as a film-forming base. The optimal concentrations of polymers that ensure the production of high-quality dosage forms have been established. The results of physical-chemical, pharmaco-technological and biopharmaceutical tests of the obtained films are presented.