Abstract
It is a well known fact that endocrine glands release all produced hormones directly into the venous blood, which immediately, via pulmonary circulation, is delivered to the lungs that have an enormous surface area. The results of our experimental and clinical studies of the levels of hormones in afferent and efferent pulmonary blood flow revealed previously unknown or unnoticed phenomena that lung tissue participate in qualitative and quantitative state of all studied hormones in general arterial blood flow in humans and experimental animals. We have also proved that central neurogenic regulation of transit, storage or release of above mentioned hormones into arterial blood is greatly influenced by physiological status of hypothalamic structures. Thus, the system of entire hormonal homeostasis is added by important and mandatory physiological unit ‐ the lungs. In our opinion this system should be viewed as: HORMONES‐ VENOUS CIRCULATION‐ LUNGS‐ ARTERIAL CIRCULATION‐TARGET TISSUES. It is not unreasonable to assume that by influencing respiratory function we can influence the level of hormones in the entire organism. If this theory is proved to be correct the simple but effective therapeutic modalities of changing frequency of respirations or holding the breaths can be used in treatment of multitude of pathophysiological conditions.