Abstract
The papre presents the results of studies of antibiotic resistance of opportunistic and pathogenic microflora Escherichia coli, Salmonella spp., S. aureus isolated from raw materials and products of animal origin. An analysis is given of the content of pathogenic and opportunistic microorganisms in meat products in order to ensure their safety for humans. Bacteriological and molecular genetic studies were carried out at the Research Institute of Applied Biotechnology of Kostanay Regional University named after A. Baitursynov in 2020–2021. The material for research was samples of raw and ready-to-eat food products selected in farms (milk), in the trade network and at public catering establishments in the Kostanay Region. A total of 409 food samples were subjected to the study, of which 76 microorganisms were isolated and identified, among them 28 strains – E. coli, 2 strains – Salmonella spp., 46 – S. aureus. All studied microorganisms showed resistance to at least one antibacterial drug, most of the studied strains had polyresistance. The results of research showed that raw meat is less contaminated with pathogenic microflora than semi-finished products prepared from it. There is an assumption that pathogenic microflora can penetrate into finished products and semi-finished products in an exogenous way (through environmental objects, biological agents), by contact infection according to the “animal–human” and “human–human” schemes, in case of violation of the sanitary and hygienic regime when production and storage of meat products. The results obtained indicate that pathogens of enteropathogenic diseases circulating on the territory of the Kostanay Region of the Republic of Kazakhstan, possessing not only phenotypic, but also genotypic resistance to antibacterial drug