Properties of bentonite and local anesthetics composition

Shynar Zhumagaliyeva, Bates Malikovna Kudaibergenova, M. K. Beisebekov, Zharylkasyn A. Abilov

2007

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DOI 10.1002/app.26311
Data confidence 70 medium
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Abstract

Abstract The interaction of the bentonite of the Manrak deposit of the East‐Kazakhstan region with the AK‐29 and richlokain local anesthetics has been studied to synthesize the new prolonged medical compounds. The methods of equilibrium swelling, sedimentation, electrophoresis, rotational viscosimetry, and IR spectroscopy have been used. The comparative analysis of interaction of bentonite clay with medical compounds has been carried out. The dependence of interaction nature on an anesthetic structure has been observed. Results of anesthetic release from polymer show a high degree of their fixation and prolongation. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2007