Chronic Obstructive Pulmonary Disease as a Factor of Unfavorable Cardiovascular Prognosis After Percutaneous Coronary Interventions in Ischemic Heart Disease

2015

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DOI 10.18565/cardio.2015.10.41-45
Data confidence 70 medium
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Abstract

AIM: to elucidate effect of concomitant chronic obstructive pulmonary disease (COPD) on remote results of percutaneous coronary intervention (PCI) with stent implantation in patients with ischemic heart disease (IHD). MATERIAL AND METHOD: We analyzed data of long term follow-up of 346 IHD patients after PCI with stenting. Groups of patients with and without COPD had comparable baseline clinical and functional characteristics. During follow-up we registered cardiovascular events (cardiovascular death, myocardial infarction, stroke, revascularization), as well as time to first event with the construction of Kaplan-Meier curves. RESULTS: Difference in relative frequency of occurrence of studied events between groups was not significant (24 and 17% among patients with and without COPD respectively, p=0.13), but in patients with COPD events occurred significantly earlier (p=0.02). Patients with adverse cardiovascular events during follow-up at baseline had lower exercise tolerance and glomerular filtration rate, more often had diabetes.