Modern achievements in genetic studies of idiopathic generalized epilepsies

2018

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DOI 10.17116/jnevro201811810256
Data confidence 70 medium
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Abstract

The review presents modern data on the genetics of idiopathic generalized epilepsies. Identified genes encode different structures of neurons, including voltage-dependent channels, receptors of neurotransmitters, protein-associated ion channels and synaptic proteins. The authors describe already identified genes, which are a causative factor of idiopathic generalized epilepsies and discuss further prospects of using molecular genetic studies.