A New Flavonol Glycoside from Limonium gmelinii

ZA Kozhamkulova, MM Radwan, GE Zhusupova, ZZ Abilov, Saniya N. Rahadilova, Samir Anis Ross

2010

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DOI 10.1055/s-0030-1251829
Data confidence 70 medium
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Abstract

Gmelinoside I (1), a new flavonol glycoside, was isolated and chemically characterized as 3,5,7,3′,4′,5′-hexahydroxy-3-O-α-D-galactopyranosylflavone from the aerial part of Limonium gmelinii (Plumbaginaceae) by UV, IR, ID and 2D NMR and HRESIMS experiments. Five compounds (2–6) were also isolated and identified as, (-)-epigallocatechin-3-O-gallate (2), myricetin (3), myricetin-3-O-α-L-rhamnopyranoside (4), myricetin-3-O-β-D-galactoside-6((Prime))-O-gallate (5) and caprolactam (6). The antibacterial, antifungal and antileishmanial activities [1] of the isolated compounds were evaluated. Fig.1 Acknowledgments: Z.A.K is thankful for Kazakhstan government for financial support. We are grateful to Drs. Bharathi Avula, Melissa Jacob and Babu Tekwani, National Center for Natural Products Research for assistance with the HRESIMS, antimicrobial and antileishmanial assays respectively. References: [1] Radwan MM, Manly SP, et al. (2007) Nat Prod Comm 2: 901–904.