Occupation and chronic obstructive pulmonary disease in Minsk tractor plant workers

Denis Vladimirovich Vinnikov, Sergey Semizhon, Tatsyana Rybina, Liudmila Savich, Vicktor Scherbitsky, И. А. Маничев

2017

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DOI 10.1002/ajim.22776
Data confidence 70 medium
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Abstract

Background The aim of this study was to measure the association of exposure to dust at workplace with COPD using objective methods of exposure and outcome classification. Methods Forced expiratory volume in one second (FEV1) to forced vital capacity (FVC) <70%; FVC below LLN, and FEV1 below LLN from the annual screening of Minsk Tractor Plant workers (N = 458) were tested for predictors in an adjusted logistic regression model. Results In a regression model, adjusted for pack‐years of smoking, age, sex, and work duration, work in highly exposed workplaces was associated with FEV1/FVC<70% (odds ratio (OR) 2.10 (95% confidence interval (CI) 1.16;3.83); and FEV1 Conclusions Workers in highly exposed to dust workplaces had double odds of developing COPD.