Abstract
According to the International Bureau of Epizootics, until recently, the territory of Kazakhstan was considered a free zone from foot-and-mouth disease in animals with vaccination, but there is a risk of the disease virus being introduced from cross-border countries into our republic. Therefore, the veterinary service and scientific community of our state need to conduct constant monitoring with seromonitoring and screening of the immune status of animals throughout the country.It is known that outbreaks of foot and mouth disease cause significant damage to livestock production and the economy of the Republic of Kazakhstan when the virus is likely to be introduced from disadvantaged countries led to the emergence of multiple foci of infection in the country and huge costs for their elimination.The introduction of foot-and-mouth disease into the regions of Kazakhstan that are part of the zone free from foot-and-mouth disease without vaccination, officially recognized by the World Organization for Animal Health, led to the suspension of the status of the entire zone, which in turn led to restrictions on both the export of livestock products and grain, and on trade inside the countryThe purpose of our study is to determine the seroprevalence of foot and mouth disease in Kazakhstan for 2021-2023.It has been established that there is still a high risk of introducing new genotypes of the foot-and-mouth disease virus into the territory of our country.