The use of atypical antipsychotics in the therapy of depressive episodes in patients with bipolar disorder

E. A. Strel’tsov

Medical Herald of the South of Russia, 2021

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DOI 10.21886/2219-8075-2021-12-3-32-35

Data confidence 70 medium

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Abstract

This literature review addresses the effi cacy and safety of atypical antipsychotics in patients with bipolar depression. Th e results of randomized studies and systematic meta-analyses of recent years were revised in detail. The effi cacy of the drug intake was reviewed for the following key research points: Clinical General Impression of Condition Severity Scale (CGI-S) and Montgomery-Asberg Depression Rating Scale (MADRS). A systematic literature search was carried out using Scopus, Web of Science, MedLine, elibrary, and other databases.